Would it be possible to implement a USB-to-UART bridge that shows up on USB-CDC similar to how the MCP2221a has the USB-HID and USB-CDC which maps the TX and RX pins to /dev/ttyACM0 on your laptop?
I found this project https://github.com/Noltari/pico-uart-bridge but I would like to combine that functionality with the u2if firmware.