I'm getting RemoteSystemUnavailable error when trying to connect or launch urls to a PC running 1809, if that PC is available via proximity. (However, when it's not available via proximity and is using cloud, it's fine)
This issue has been reported by my app's users on Android->Windows and Windows Mobile->Windows scenarios.
And it seems that Windows 10 version 1809 is only affected, and 1803 is fine.