Skip to content
View edwin5588's full-sized avatar

Block or report edwin5588

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please don't include any personal information such as legal names or email addresses. Markdown supported. This note will be visible to only you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
edwin5588/README.md

Hi there πŸ‘‹

Hi, I’m Edwin β€” an AI / Machine Learning Engineer with 3+ years of experience building and deploying production ML systems. I specialize in applied machine learning, ML pipelines, and LLM-powered tools data-intensive applications, with a focus on reliability, scalability, and real-world impact.

🌐 Selected Projects

Production AI assistant integrated into the GenePattern platform, supporting multimodal data analysis, workflow automation, and researcher productivity at scale.

Stack: Python Β· LangChain Β· AWS Β· LLMs

Interactive portal for exploring extrachromosomal DNA (ecDNA) across cancer samples.

Stack: Django Β· MongoDB Β· JS


Engineering Focus

  • Production ML pipelines and reproducible workflows
  • Applied ML for biomedical and health data
  • GPU acceleration and performance optimization
  • LLM integration into real-world systems

πŸ“š Selected publications and production engineering contributions in large-scale biomedical ML systems

Luebeck J, Huang E, et al.
AmpliconSuite: Analyzing Focal Amplifications in Cancer Genomes.
Genomics and Informatics, 2024.
πŸ”— ScienceDirect
β†’ Deployed ML pipelines and a cloud-hosted repository for large-scale ecDNA analysis, enabling reproducible research across 20 + projects (funded >$25 M).


Liefeld T, Huang E, Wenzel A, Yoshimoto K, Sharma A, Sicklick J, Mesirov J, Reich M.
NMF Clustering: Accessible NMF-based Clustering Utilizing GPU Acceleration.
Genomics and Informatics, 2024.
πŸ”— Fortune Journals
β†’ Implemented RAPIDS AI, CuPy, and custom CUDA kernels to achieve 27Γ— runtime speedup on HPC clusters.


Reich M, Tabor T, Liefeld J, Joshi J, Kim F, Huang E, Thorvaldsdottir H, Blankenberg D, Mesirov J.
Genomics to Notebook (g2nb): Extending the Electronic Notebook to Address the Challenges of Bioinformatics Analysis.
Genomics and Informatics, 2024.
πŸ”— Fortune Journals
β†’ Contributed to extending Jupyter-based infrastructure (g2nb) for scalable bioinformatics workflows.


Reich M, Tabor T, Liefeld J, Huang E, Kim F, Mesirov J.
The GenePattern Ecosystem for Cancer Bioinformatics.
AACR Cancer Research (Abstract 7426), 2024.
πŸ”— AACR Abstract
β†’ Presented cloud-based GenePattern workflows supporting cancer informatics and LLM integration.

Pinned Loading

  1. genepattern/AmpliconSuite genepattern/AmpliconSuite Public

    Forked from edwin5588/paa_custom

    Wraps the AmpliconSuite-pipeline workflow to identify one or more connected genomic regions which have copy number amplifications.

    Python 1

  2. genepattern/nmf-gpu genepattern/nmf-gpu Public

    GPU-optimized NMF and variations

    Python 4

  3. AmpliconSuite/AmpliconRepository AmpliconSuite/AmpliconRepository Public

    Website to host AmpliconSuite outputs, including AA outputs and resulting focal amplification classifications, such as ecDNA.

    HTML 4 5